Multiple loop heat pipes which have two evaporators and two condensers in one loop are a kind of active heat transfer device. Since they have two evaporators and two condensers, the operating mode also becomes multiple. This work discusses the cases that multiple loop heat pipes were operated with one condenser at high temperature and the other at low temperature. To avoid the high temperature returning liquid and keep the multiple loop heat pipes work properly, the flow regulator which was (...) made of polyethylene was designed, fabricated and applied in this test. The effect of flow regulator was confirmed and analyzed. In the test that large temperature difference existed between two sinks, it can be found according to the result that the flow regulator worked effectively and prevented the high temperature vapor to enter the inlet of common liquid line, which can keep the evaporators and returning liquid to operate at low temperature. With the increment of heat loads and the temperature difference between two sinks, the pressure difference between two condensers became larger and larger. When the pressure difference was larger than the flow regulator’s capillary force, the flow regulator could not work properly because the high temperature vapor began to flow through the flow regulator. According to the test data, the flow regulator can work properly within the sinks’ temperature 0?C/60?C and the two evaporators’ heat load 30/30 W. (shrink)